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Stem cell mobilizers
Stem cell mobilizers
Agents used to mobilize stem cells bind to the chemokine receptor CXCR4 and inhibit the binding of stromal cell-derived factor-1-alpha (SDF-1-alpha) which leads to the mobilization of hematopoietic stem cells to the peripheral blood. This means stem cells can be more easily collected from peripheral blood for stem cell transplant.
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