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Stem cell mobilizers

Agents used to mobilize stem cells bind to the chemokine receptor CXCR4 and inhibit the binding of stromal cell-derived factor-1-alpha (SDF-1-alpha) which leads to the mobilization of hematopoietic stem cells to the peripheral blood. This means stem cells can be more easily collected from peripheral blood for stem cell transplant.

Stem cell mobilizers

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