All content on this site is intended for healthcare professionals only. By acknowledging this message and accessing the information on this website you are confirming that you are a Healthcare Professional. If you are a patient or carer, please visit Know AML.
The AML Hub uses cookies on this website. They help us give you the best online experience. By continuing to use our website without changing your cookie settings, you agree to our use of cookies in accordance with our updated Cookie Policy
Hedgehog pathway inhibitors
Hedgehog pathway inhibitors
The Hedgehog pathway is essential for cell growth and differentiation in embryonic development. Its reactivation in adult tissues stimulates tissue repair or cell proliferation and is often associated with malignancies. Hedgehog pathway inhibitors block the pathway by binding to the Hedgehog-ligand cell surface receptors. Examples of Hedgehog pathway inhibitors include vismodegib, sonidegib, and glasdegib.
|||