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EHA2026 Congress | Top abstracts: What’s hot in AML?

By Sari Cumming

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Jun 9, 2026

Learning objective: After reading this article, learners will be able to cite new clinical developments in acute myeloid leukemia.


To help navigate the exciting content being presented at the European Hematology Association (EHA) 2026 Congress, June 11–14, 2026, Stockholm, SE, the AML Hub Steering Committee members have provided their recommendations for the top abstracts to look out for in AML. 

EHA2026 | Top abstracts in AML

Oral presentations: Thursday, June 11 
Abstract  Title Presenter Time (CEST) 
S126 Opti-AML: Prospective randomized phase 2 trial of 28 versus 14 day schedule of venetoclax and azacitidine for 2 cycles in newly diagnosed genomically agnostic acute myeloid leukemia patients ≥60 years Uma Borate 17:00–17:15 
S127 A multicenter phase 1b/2 trial of azacitidine, venetoclax, and ivosidenib in IDH1-mutated acute myeloid leukemia (AML) Jennifer Marvin-Peek 17:15–17:30 
S128 Venetoclax and azacitidine for molecular failure intervention as a bridge-to-transplant strategy for NPM1-mutated acute myeloid leukemia: The GIMEMA AML2521 phase 2 trial Chiara Sartor 17:30–17:45 
S129 Prospective NAMLG LD-VenEx trial: Azacitidine in combination with reduced duration of venetoclax in patients with de novo, secondary, and relapsed/refractory acute myeloid leukemia Anne Louise Tølbøll Sørensen 17:45–18:00 
S136 Impact of two versus three chemotherapy cycles before HSCT in MRD-negative pediatric AML: A multicenter retrospective study Lindsey Murphy 17:00–17:15 

 

Oral presentations: Friday, June 12 
Abstract  Title Presenter Time (CEST) 
S170 CPX-351 versus standard of care as bridging to alloHCT in patients with higher-risk myelodysplastic neoplasms or oligoblastic acute myeloid leukemia: Results of the randomized phase 2 PALOMA study Uwe Platzbecker 17:15–17:30 
S327 Prognostic importance of pre-treatment health-related quality of life and fitness indicators in older adults with acute myeloid leukemia. Analysis from the international EORTC AML 21 phase 3 trial Fabio Efficace 17:45–18:00 

 

Oral presentations: Saturday, June 13 
Abstract  Title Presenter Time (CEST) 
LB5007 First-in-class switchable allogeneic CAR-T therapy for CD123+ AML – Results from the phase IA REVSTAR-123 (AVC-201-01) study Martin Wermke 13:15–13:30 
S260 Integrated metabolic and epigenetic profiling uncovers distinct immune‑escape programs and targetable vulnerabilities in post‑transplant AML relapse Annalisa Tameni 17:15–17:30 
S274 A genetic–clinical prognostic algorithm for risk stratification in patients with relapsed/refractory acute myeloid leukaemia undergoing allogeneic haematopoietic stem cell transplantation Yue Jin 18:15–18:30 

 

Oral presentations: Sunday, June 14 
Abstract  Title Presenter Time (CEST) 
LB5005 Gilteritinib versus midostaurin in patients with newly diagnosed FLT3-mutated acute myeloid leukemia eligible for intensive therapy: Results from the phase 3 HOVON156/AMLSG28-18/PASHA trial Marc Raaijmaker 10:15–10:30 
S130 Ziftomenib combined with intensive induction (7+3) for newly diagnosed NPM1‑m or KMT2A-r acute myeloid leukemia (AML): Long-term results from the KOMET-007 trial Amer M. Zeidan 11:00–11:15 
S131 A phase II randomized study of AK117 versus placebo in combination with venetoclax and azacitidine in previously untreated acute myeloid leukemia patients ineligible for intensive chemotherapy Huafeng Wang 11:15–11:30 
S133 Intensive chemotherapy in combination with quizartinib versus midostaurin for FLT3-ITD mutated acute myeloid leukemia: A multicenter cohort study Michelle Lee 11:45–12:00 
S134 TUSCANY study of safety and efficacy of tuspetinib plus standard of care venetoclax and azacitidine in study participants with newly diagnosed AML ineligible for induction chemotherapy Nikolai Podoltsev 12:00–12:15 

 

Posters  
Abstract  Title Presenter Date and time (CEST) 
PF489 Revumenib + intensive chemotherapy for newly diagnosed acute myeloid leukemia harboring genetic alterations in KMT2A, NPM1, or NUP98: Updated phase 1 results from SNDX-5613-0708 Ibrahim Aldoss Friday, June 12, from 18:45 
PF495 Phase 1/2 study of the all-oral combination of revumenib (SNDX-5613) with decitabine/cedazuridine (ASTX727) and venetoclax (SAVE) in relapsed/refractory AML Branko Cuglievan Friday, June 12, from 18:45 
PF509 Triplet therapy with quizartinib, decitabine, and venetoclax in newly diagnosed and relapsed/refractory FLT3-ITD acute myeloid leukemia Musa Yilmaz Friday, June 12, from 18:45 
PF514 Efficacy of revumenib in acute myeloid leukemia harboring NPM1-mutated co-mutations: Post hoc analysis of AUGMENT-101 James S. Blachly Friday, June 12, from 18:45 
PF521 Impact of prior induction cycle number on outcomes with gilteritinib in relapsed/refractory FLT3-mutated AML: A pooled post-hoc analysis of ADMIRAL and COMMODORE studies Mark Levis Friday, June 12, from 18:45 
PF536 Real-world management practices with venetoclax-based therapy for AML - Results from the prospective REVIVE study Yakir Moshe Friday, June 12, from 18:45 
PF542 Revumenib in the real world: Interim findings from the ROAR study in relapsed/refractory acute leukemia Shai Shimony Friday, June 12, from 18:45 
PF550 A phase I/II study of gilteritinib and momelotinib in adults with relapsed or refractory FLT3-mutated acute myeloid leukemia Nicholas Short Friday, June 12, from 18:45 
PF555 No evidence of QTc interval prolongation with the menin inhibitor bleximenib when given as monotherapy or in combination with AML-directed therapies for KMT2A or NPM1 altered AML Maher Abdul-Hay Friday, June 12, from 18:45 
PS1512 Ultra-high-sensitivity next-generation sequencing–based MRD predicts outcome in intensively treated older patients with acute myeloid leukemia: Results from the ALFA-1200 cohort Augustin Boudry Saturday, June 13, from 18:45 
PS1599 ALIDHE: A phase 3b study assessing ivosidenib + azacitidine in adults with newly diagnosed mIDH1 acute myeloid leukaemia who are ineligible for intensive induction chemotherapy Paresh Vyas Saturday, June 13, from 18:45 
PS1607 Clinical activity of revumenib in patients with relapsed/refractory (R/R) NUP98-rearranged acute leukemias Ghayas Issa Saturday, June 13, from 18:45 
PS1617 Real-world outcomes in MECOM-rearranged AML: The largest multicenter cohort reported to date Cecilia Arana Yi Saturday, June 13, from 18:45 
PS1621 Phase I/phase 2 study of quizartinib combined with CLIA in newly diagnosed and relapsed/refractory FLT3-mutated and wild-type acute myeloid leukemia Musa Yilmaz Saturday, June 13, from 18:45 
PS1627 Long-term follow up of oral decitabine/cedazuridine (ASTX727) plus venetoclax in newly diagnosed acute myeloid leukemia: A phase 2 study Thura Win Htut Saturday, June 13, from 18:45 
PS1631 Revumenib therapy post hematopoietic stem cell transplant for patients with relapsed/refractory KMT2Ar, NPM1m, and NUP98r acute myeloid leukemia: Post hoc analysis of outcomes from AUGMENT-101 Andrius Žučenka Saturday, June 13, from 18:45 

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