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Courtney DiNardoDuring the 2022 ASCO Annual Meeting, the AML Hub spoke with Courtney DiNardo, MD Anderson Cancer Center, Houston, US. We asked, What factors affect how a patient responds to ivosidenib treatment?
What factors affect how a patient responds to ivosidenib treatment?
DiNardo begins by outlining important factors when using ivosidenib in the single-agent relapse setting and the new information we have learned from the AGILE trials, which combined ivosidenib with azacitidine. DiNardo notes that, although patients with complex cytogenetics appeared to have less benefit, more data is needed to draw conclusions.
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Approximately what proportion of your patients with FLT3-mutations also have NPM1 and DNMT3A co-mutations?