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2022-11-21T11:29:25.000Z

Visual Abstract | Venetoclax plus azacitidine for patients with IDH1/2 mutated AML who are ineligible for intensive chemotherapy

Nov 21, 2022
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Learning objective: After reading this article, learners will be able to cite a new development in the treatment of patients with IDH1/IDH2-mutated AML

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The AML Hub is delighted to present a visual abstract representing key data pooled from the phase III Viale-a trial (NCT02993523) and a phase Ib trial (NCT02203773) investigating the efficacy and safety of venetoclax plus azacitidine and azacitidine monotherapy in treatment-naïve patients with acute myeloid leukemia (AML) who are ineligible for intensive chemotherapy. This analysis will focus on isocitrate dehydrogenase (IDH) 1/2 mutational status; however, an overview of the Viale-a trial has been previously reported by the AML Hub, as well as articles on MRD response and TP53 mutational status.


Visual Abstract

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