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Magrolimab in TP53-mutated AML and MDS: What are the latest updates from EHA2022?

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Jul 8, 2022
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Learning objective: After reading this article, learners will be able to cite a new clinical development in AML

During the EHA2022 Congress, the AML Hub spoke with Naval Daver, MD Anderson Cancer Center, Houston, US. We asked for the latest updates about magrolimab in TP53-mutated AML and MDS from EHA2022.

Magrolimab in TP53-mutated AML and MDS: What are the latest updates from EHA2022?

Daver discusses a study investigating magrolimab + azacitidine in two patient groups: (1) patients with frontline higher-risk MDS and (2) older patients with AML who are unfit for intensive chemotherapy. Daver discusses the mechanism of action of magrolimab and concludes by outlining efficacy, survival, and adverse effects seen in both study arms.