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What does real-world data tell us about frontline therapy with CPX-351 vs venetoclax + azacitidine?

Featured:

Andrew Matthews

Feb 2, 2022


During the 63rd ASH Annual Meeting and Exposition, the AML Hub was pleased to speak with Andrew Matthews, University of Pennsylvania, Philadelphia, US. We asked, What does real-world data tell us about frontline therapy with CPX-351 vs venetoclax and azacitidine?

What does real-world data tell us about frontline therapy with CPX-351 vs Ven + Aza?

Matthews begins by outlining the background for this study, presented at ASH, where the primary outcome of overall survival (OS) was directly compared for CPX-351 vs Ven + Aza. He discusses results of the study and various analyses of these results. Matthews highlights that since at this point there are not yet significant differences in OS between the two therapies, adverse events are key in decision making.