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Visual abstract | Phase II trial of tamibarotene combination therapy in patients with newly diagnosed AML

Feb 3, 2023
Learning objective: After reading this article, learners will be able to describe new advancements in the treatment of patients with newly diagnosed AML.

The AML Hub is delighted to present a visual abstract summarizing key preliminary data from a phase II trial (NCT02807558) investigating the safety and efficacy of tamibarotene combination therapy in newly diagnosed adult patients with acute myeloid leukemia who are unfit for intensive chemotherapy. Tamibarotene is an oral, selective retinoic acid receptor alpha (RARα) agonist that received orphan drug designation from the U.S. Food and Drug Administration (FDA) in 2017 and has been previously discussed on by the AML Hub. This study compared response rates and survival outcomes in patients who were RARA-positive to patients who were RARA-negative.


Visual Abstract

To download this visual abstract, click below.

Download here


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