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Treatment options available for transplant ineligible relapsed AML patients after ven + aza therapy?

By Addy Dullaghan

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Thomas Cluzeau

Feb 14, 2022


The AML hub was pleased to speak with Thomas Cluzeau, Université Côte d’Azur, Nice, France. We asked, What are the treatment options available for transplant ineligible relapsed AML patients following venetoclax + azacitidine therapy?

Treatment options available for transplant ineligible relapsed AML patients after ven + aza therapy?

Cluzeau begins by discussing studies presented at previous ASH meetings, such as the IDEAL trials, and their promising results. He highlights the importance of determining AML subtypes and outlines research focused on treatments for IDH1 and IDH2 mutated AML. Finally, he describes current trials as well as future developments, such as immunotherapies.

 

Your opinion matters

When treating a patient newly diagnosed with IDH1-mutated AML who is ineligible for intensive chemotherapy, which initial treatment approach would you most likely consider?