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The role of menin in the pathogenesis of AML

By Sari Cumming

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Oct 1, 2025

Learning objective: After reading, learners will understand how menin inhibitors disrupt a key mechanism in the pathogenesis of AML and the current clinical trial landscape for menin inhibitors in AML.


Do you know... What is the primary mechanism of action of menin inhibitors in the treatment of acute myeloid leukemia?

AML Hub spotlight: We explore the role of menin in acute myeloid leukemia pathogenesis and review the latest clinical trial data of menin inhibitors, which demonstrate clinically meaningful responses in acute myeloid leukemia. 

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