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Risk stratification and guidelines in AML management

By Dylan Barrett

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Naval DaverNaval DaverGail J. RobozGail J. Roboz

Jan 25, 2024

Learning objective: After reading this article, learners will be able to cite a new development in the treatment of AML


The AML Hub was pleased to speak to Gail Roboz, Weill Cornell Medicine, New York, US, and Naval Daver, MD Anderson Cancer Center, Houston, US. We asked about risk stratification and guidelines in acute myeloid leukemia (AML) management.

Risk stratification and guidelines in AML management

Firstly, Roboz and Daver discuss the impact of blast count on the diagnosis of AML and how a patient's mutational profile can affect treatment decisions. They highlight available, effective lower-intensity and targeted therapies and a potential transition to a fully genomic- and cytogenetic-based classification of AML. Finally, they discuss current patient selection strategies for intensive induction chemotherapy and future directions in AML treatment.