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LYT-200 granted Orphan Drug Designation by the U.S. FDA
On March 13, 2024, the U.S. Food and Drug Administration granted Orphan Drug Designation to LYT-200, a fully human immunoglobulin G4 monoclonal antibody targeting galectin-9, for the treatment of patients with acute myeloid leukemia.1 LYT-200 is currently being evaluated in a phase Ib trial (NCT05829226), as a monotherapy and in combination with venetoclax plus hypomethylating agents, for the treatment of patients with relapsed/refractory acute myeloid leukemia and myelodysplastic syndromes.1
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