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Treating classical Hodgkin lymphoma: Spotlight on targeted therapies
with Gilles Salles, Paul Bröckelmann, and Ann S. LaCasce
Saturday, November 2, 2024
8:50-9:50 CET
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What are the latest updates from the phase III QuANTUM-First trial?
Erba discusses the QuANTUM-First trial (NCT02668653) assessing the addition of quizartinib vs placebo to standard chemotherapy and continuation therapy in adult patients aged 18–75 years with newly diagnosed FLT3-internal tandem duplication mutated acute myeloid leukemia. He continues by delving into response rates, survival outcomes, and safety data from the trial; outlining the factors that could influence responses. Erba compares the findings of QuANTUM-First with the phase III RATIFY trial (NCT00651261), which investigated the addition of midostaurin to standard chemotherapy in patients with FLT3-mutated AML.
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