The aml Hub website uses a third-party service provided by Google that dynamically translates web content. Translations are machine generated, so may not be an exact or complete translation, and the aml Hub cannot guarantee the accuracy of translated content. The aml and its employees will not be liable for any direct, indirect, or consequential damages (even if foreseeable) resulting from use of the Google Translate feature. For further support with Google Translate, visit Google Translate Help.
The AML Hub is an independent medical education platform, sponsored by Astellas, Daiichi Sankyo, Johnson & Johnson, Kura Oncology and Syndax, and has been supported through educational grants from Bristol Myers Squibb and the Hippocrate Conference Institute, an association of the Servier Group. The funders are allowed no direct influence on our content. The levels of sponsorship listed are reflective of the amount of funding given. View funders.
Now you can support HCPs in making informed decisions for their patients
Your contribution helps us continuously deliver expertly curated content to HCPs worldwide. You will also have the opportunity to make a content suggestion for consideration and receive updates on the impact contributions are making to our content.
Find out more
Create an account and access these new features:
Bookmark content to read later
Select your specific areas of interest
View aml content recommended for you
Naval DaverDuring the 2020 Annual Meeting of the Society of Hematologic Oncology (SOHO), the AML Hub was pleased to speak to Steering Committee Member Naval Daver, MD Anderson Cancer Center, Houston, US, about gilteritinib for the treatment of FLT3 AML.
Gilteritinib in FLT3 AML
Gilteritinib is a FLT3 inhibitor which is FDA approved for the treatment of R/R FLT3-mutated AML. This approval was based on the phase III ADMIRAL trial, which evaluated gilteritinib vs investigator-choice chemotherapy. Data from the ADMIRAL study show that gilteritinib demonstrated a positive outcome for both of the study primary endpoints (overall survival and complete remission/complete remission with partial hematologic recovery).
Naval Daver concludes by outlining the next steps for gilteritinib in the AML setting.