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Ali BazarbachiDuring the 49th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), the AML Hub was pleased to speak with Ali Bazarbachi, American University of Beirut, Beirut, LB. We asked, Does the mutational profile impact outcomes following transplant?
Does the mutational profile impact outcomes following transplant?
Bazarbachi begins by describing the main genetic aberrations included in the European LeukemiaNet 2022 revised genetic-risk classifications of acute myeloid leukemia and the potential prognostic value of different gene-gene interactions in patients undergoing allogeneic hematopoietic stem cell transplant. Bazarbachi then details findings from a retrospective registry-based multicenter analysis from the EBMT on the distribution of mutation frequency and survival outcomes in patients with acute myeloid leukemia who received allogeneic hematopoietic stem cell transplant.
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Approximately what proportion of your patients with FLT3-mutations also have NPM1 and DNMT3A co-mutations?
