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What are the future prospects for FLT3 mutated AML?

During the Society of Hematologic Oncology (SOHO) 2021 Annual Meeting, the AML Hub spoke to Alexander Perl, University of Pennsylvania, Philadelphia, US. We Asked, What are the future prospects for FLT3 mutated acute myeloid leukemia (AML)?

What are the future prospects for FLT3 mutated AML?

Perl begins by outlining the standard of care for patients being treated intensely with newly diagnosed AML and upcoming studies investigating FLT3 inhibitors such as midostaurin, sorafenib, quizartinib, and gilteritinib. He goes on to discuss treatment prospects for patients ineligible for intensive chemo and post transplant maintenance. Finally, he highlights the importance of upcoming study MORPHO, which investigates gilteritinib as posttransplant maintenance.