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The AML is pleased to present a visual abstract summarizing results from the phase III ASTRAL-2 trial (NCT02920008) assessing guadecitabine, a next-generation hypomethylating agent vs standard-of-care treatment in patients with relapsed/refractory acute myeloid leukemia. Results from this trial were published by Roboz et al.1 in Blood Advances.
Guadecitabine was associated with a higher rate of clinical response, and while overall survival was not improved, a survival benefit was observed in several prespecified subgroups.1.
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