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Should Venetoclax based induction regimens be considered SOC for 60+ adults?

During the 3rd NCRI AML Academy, the AML Hub was pleased to speak with David Taussig, The Royal Marsden Hospital, London, UK. We asked, Should Venetoclax based induction regimens be considered standard of care for 60+ adults?

Should Venetoclax based induction regimens be considered SOC for 60+ adults?

Taussig begins by highlighting that for adults not fit for intensive chemotherapy, evidence favors the use of venetoclax + azatadine. He goes on to outline AML subtypes that can benefit from venetoclax regimens in fit patients, discussing FLT-3 mutations and the BELLINI trial.

 

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