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Joshua Zeidner | ASH 2018 | Biomarker-guided phase II study in MCL-1 dependent R/R AML patients
At the 2018 American Society of Hematology meeting, Joshua Zeidner from the University of North Carolina, Chapel Hill, US, talks about the results from the stage 1 portion of the Zella 201 trial in which the efficacy and safety of alvocidib, in combination with cytarabine and mitoxantrone was evaluated in MCL-1 dependent relapsed or relapsed acute myeloid leukemia (AML) patients.
Alvocidib given before cytarabine and mitoxantrone in MCL-1-dependent AML has clinical activity, particularly in those refractory to frontline therapy.
Biomarker-guided phase II study in MCL-1 dependent R/R AML patients
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