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How do you treat AML that has evolved from MPD?

During the Acute Leukemia Forum 2021, the AML Hub spoke to Raajit K. Rampal, Memorial Sloan Kettering Cancer Center, New York, US. We asked, How do you treat AML that has evolved from myeloproliferative disorders (MPD)?

How do you treat AML that has evolved from MPD?

Historically, patients who evolve from MPD to AML tend to have the worst prognosis among all AML subtypes due to their genomic profile. In this video, Rampal discusses treatment approaches in this setting. He believes there is an unmet need in this population, so patients with post-MPD AML should be prioritized in clinical trials, where possible.

 

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