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During the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, the AML Hub spoke to Jacqueline Garcia, Dana-Farber Cancer Institute, Boston, US. We asked, Does the addition of venetoclax to low-dose conditioning improve outcome after allogeneic hematopoietic stem cell transplantation (allo-HSCT)?
Does the addition of venetoclax to low-dose conditioning improve outcome after allo-HSCT?
Garcia reports the results of the dose-escalation and expansion cohorts from a phase I study investigating the safety and efficacy of adding venetoclax to fludarabine and busulfan reduced intensity conditioning chemotherapy prior to allo-HSCT in patients with high-risk myeloid malignancies.
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