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Nigel RussellDuring the 25th Congress of the European Hematology Association (EHA), the AML Hub spoke to Nigel Russell, Guy's and St Thomas' NHS Foundation Trust, London, UK. We asked: How should gemtuzumab ozogamicin be applied in AML?
Here, Nigel Russell discusses the treatment of elderly patients with AML with the CD33-targeted antibody–drug conjugate, gemtuzumab ozogamicin, as part of the AML18 trial. The overall survival and response rates demonstrated by patients, who were randomized to receive either a single dose or a fractionated dosing schedule of gemtuzumab ozogamicin, are outlined.
AML18 trial: How should gemtuzumab ozogamicin be applied in AML?
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