Chromosomal aberrations
BCR-ABL1
CBFB-MYH11
Core binding factor
KMT2A rearranged
MLLT3-KMT2A
Myelodysplasia-related
Normal cytogenetics
Promyelocytic leukemia
Cohesin mutations
RAD21
SMC1A
SMC3
STAG1
STAG2
Epigenetic modifier mutations
ASXL1
DNMT3A
EZH2
IDH1
IDH2
TET2
Nucleophosmin mutations
NPM1
Origin
De novo
Secondary
Therapy-related
Signaling pathway mutations
FLT3-ITD
FLT3-TKD
KIT
KRAS
NF1
NRAS
PTPN11
Spliceosome mutations
SF3B1
SRSF2
U2AF1
ZRSR2
Transcription factor mutations
CEBPA
GATA2
RUNX1
Tumor suppressor mutations
TP53
WT1